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Genomic analysis of 63,220 tumors reveals insights into tumor uniqueness and targeted cancer immunotherapy strategies

BACKGROUND: The integration of genomics with immunotherapy has potential value for cancer vaccine development. Given the clinical successes of immune checkpoint modulators, interest in cancer vaccines as therapeutic options has been revived. Current data suggest that each tumor contains a unique set...

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Detalles Bibliográficos
Autores principales: Hartmaier, Ryan J., Charo, Jehad, Fabrizio, David, Goldberg, Michael E., Albacker, Lee A., Pao, William, Chmielecki, Juliann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324279/
https://www.ncbi.nlm.nih.gov/pubmed/28231819
http://dx.doi.org/10.1186/s13073-017-0408-2