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Dual polarization of human alveolar macrophages progressively increases with smoking and COPD severity
BACKGROUND: It is known that tissue macrophages derive not only from blood monocytes but also from yolk sac or fetal liver, and the tissue of residence guides their function. When isolated, they lose tissue specific signatures, hence studies of human macrophages should be ideally done directly in th...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324331/ https://www.ncbi.nlm.nih.gov/pubmed/28231829 http://dx.doi.org/10.1186/s12931-017-0522-0 |