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Micro RNAs and DNA methylation are regulatory players in human cells with altered X chromosome to autosome balance

The gene balance hypothesis predicts that an imbalance in the dosage sensitive genes affects the cascade of gene networks that may influence the fitness of individuals. The phenotypes associated with chromosomal aneuploidies demonstrate the importance of gene dosage balance. We have employed untrans...

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Detalles Bibliográficos
Autores principales: Rajpathak, Shriram N., Deobagkar, Deepti D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324395/
https://www.ncbi.nlm.nih.gov/pubmed/28233878
http://dx.doi.org/10.1038/srep43235