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Loss of hSef promotes metastasis through upregulation of EMT in prostate cancer

We have previously reported that the negative signaling regulator Similar Expression to FGF (hSef) is downregulated in prostate cancer and its loss is associated with clinical metastasis. Here, we explored the mechanistic basis of this finding. We first confirmed our clinical observation by testing...

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Detalles Bibliográficos
Autores principales: Hori, Satoshi, Wadhwa, Karan, Pisupati, Venkat, Zecchini, Vincent, Ramos‐Montoya, Antonio, Warren, Anne Y, Neal, David E, Gnanapragasam, Vincent J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324539/
https://www.ncbi.nlm.nih.gov/pubmed/28073170
http://dx.doi.org/10.1002/ijc.30604