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GPR91 deficiency exacerbates allergic contact dermatitis while reducing arthritic disease in mice

BACKGROUND: Succinate, in addition to its role as an intermediary of the citric acid cycle, acts as an alarmin, initiating and propagating danger signals resulting from tissue injury or inflammatory stimuli. The contribution of this immune sensing pathway to the development of allergic and inflammat...

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Detalles Bibliográficos
Autores principales: Rubić‐Schneider, T., Carballido‐Perrig, N., Regairaz, C., Raad, L., Jost, S., Rauld, C., Christen, B., Wieczorek, G., Kreutzer, R., Dawson, J., Lametschwandner, G., Littlewood‐Evans, A., Carballido, J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324651/
https://www.ncbi.nlm.nih.gov/pubmed/27527650
http://dx.doi.org/10.1111/all.13005