Flexible and Scalable Full‐Length CYP2D6 Long Amplicon PacBio Sequencing

Cytochrome P450 2D6 (CYP2D6) is among the most important genes involved in drug metabolism. Specific variants are associated with changes in the enzyme's amount and activity. Multiple technologies exist to determine these variants, like the AmpliChip CYP450 test, Taqman qPCR, or Second‐Generati...

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Detalles Bibliográficos
Autores principales: Buermans, Henk P.J., Vossen, Rolf H.A.M., Anvar, Seyed Yahya, Allard, William G., Guchelaar, Henk‐Jan, White, Stefan J., den Dunnen, Johan T., Swen, Jesse J., van der Straaten, Tahar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324676/
https://www.ncbi.nlm.nih.gov/pubmed/28044414
http://dx.doi.org/10.1002/humu.23166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324676/
https://www.ncbi.nlm.nih.gov/pubmed/28044414
http://dx.doi.org/10.1002/humu.23166

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