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Flexible and Scalable Full‐Length CYP2D6 Long Amplicon PacBio Sequencing
Cytochrome P450 2D6 (CYP2D6) is among the most important genes involved in drug metabolism. Specific variants are associated with changes in the enzyme's amount and activity. Multiple technologies exist to determine these variants, like the AmpliChip CYP450 test, Taqman qPCR, or Second‐Generati...
Autores principales: | Buermans, Henk P.J., Vossen, Rolf H.A.M., Anvar, Seyed Yahya, Allard, William G., Guchelaar, Henk‐Jan, White, Stefan J., den Dunnen, Johan T., Swen, Jesse J., van der Straaten, Tahar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324676/ https://www.ncbi.nlm.nih.gov/pubmed/28044414 http://dx.doi.org/10.1002/humu.23166 |
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