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Transient immunological and clinical effectiveness of treating mice bearing premalignant oral lesions with PD‐1 antibodies

A carcinogen‐induced premalignant oral lesion model that progresses to oral cancer was used to examine the impact of blocking PD‐1 on cytokine expression and on progression of lesions to cancer. The results of this study show increased production of IL‐2 and the inflammatory cytokines IL‐6, IL‐17 an...

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Detalles Bibliográficos
Autores principales: Levingston, Corinne A., Young, M. Rita I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324681/
https://www.ncbi.nlm.nih.gov/pubmed/27914100
http://dx.doi.org/10.1002/ijc.30543