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NEK8 regulates DNA damage-induced RAD51 foci formation and replication fork protection

Proteins essential for homologous recombination play a pivotal role in the repair of DNA double strand breaks, DNA inter-strand crosslinks and replication fork stability. Defects in homologous recombination also play a critical role in the development of cancer and the sensitivity of these cancers t...

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Detalles Bibliográficos
Autores principales: Abeyta, Antonio, Castella, Maria, Jacquemont, Celine, Taniguchi, Toshiyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324754/
https://www.ncbi.nlm.nih.gov/pubmed/27892797
http://dx.doi.org/10.1080/15384101.2016.1259038