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Central role of PI3K–SYK interaction in fibrinogen‐induced lamellipodia and filopodia formation in platelets
The WAVE complex‐1, a complex of WAVE, Abi1, NAP1, PIR121, HSPC300, RacGTP and Arp2/3 proteins, and WASP complex‐1, a complex of WASP, Cdc42, PIP2, and Arp2/3 proteins, are involved in lamellipodia and filopodia formation, respectively. It is known that the two complexes have opposite dynamics. Furt...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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John Wiley and Sons Inc.
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324771/ https://www.ncbi.nlm.nih.gov/pubmed/28255536 http://dx.doi.org/10.1002/2211-5463.12149 |