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Central role of PI3K–SYK interaction in fibrinogen‐induced lamellipodia and filopodia formation in platelets

The WAVE complex‐1, a complex of WAVE, Abi1, NAP1, PIR121, HSPC300, RacGTP and Arp2/3 proteins, and WASP complex‐1, a complex of WASP, Cdc42, PIP2, and Arp2/3 proteins, are involved in lamellipodia and filopodia formation, respectively. It is known that the two complexes have opposite dynamics. Furt...

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Detalles Bibliográficos
Autor principal: Singh, Raghvendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324771/
https://www.ncbi.nlm.nih.gov/pubmed/28255536
http://dx.doi.org/10.1002/2211-5463.12149