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Differential Contribution of Subunit Interfaces to α9α10 Nicotinic Acetylcholine Receptor Function

Nicotinic acetylcholine receptors can be assembled from either homomeric or heteromeric pentameric subunit combinations. At the interface of the extracellular domains of adjacent subunits lies the acetylcholine binding site, composed of a principal component provided by one subunit and a complementa...

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Detalles Bibliográficos
Autores principales: Boffi, Juan Carlos, Marcovich, Irina, Gill-Thind, JasKiran K., Corradi, Jeremías, Collins, Toby, Lipovsek, María Marcela, Moglie, Marcelo, Plazas, Paola V., Craig, Patricio O., Millar, Neil S., Bouzat, Cecilia, Elgoyhen, Ana Belén
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325082/
https://www.ncbi.nlm.nih.gov/pubmed/28069778
http://dx.doi.org/10.1124/mol.116.107482