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Is there evidence that we should screen the general population for Lynch syndrome with genetic testing? A systematic review

BACKGROUND: The emerging dual imperatives of personalized medicine and technologic advances make population screening for preventable conditions resulting from genetic alterations a realistic possibility. Lynch syndrome is a potential screening target due to its prevalence, penetrance, and the avail...

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Detalles Bibliográficos
Autores principales: Prince, Anya E R, Cadigan, R Jean, Henderson, Gail E, Evans, James P, Adams, Michael, Coker-Schwimmer, Emmanuel, Penn, Dolly C, Van Riper, Marcia, Corbie-Smith, Giselle, Jonas, Daniel E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325104/
https://www.ncbi.nlm.nih.gov/pubmed/28260941
http://dx.doi.org/10.2147/PGPM.S123808