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Reparative effects of interleukin-1 receptor antagonist in young and aged/co-morbid rodents after cerebral ischemia

Neuroprotective strategies for ischemic stroke have failed to translate from bench to bedside, possibly due to the lack of consideration of key clinical co-morbidities. Stroke and co-morbidities are associated with raised levels of the pro-inflammatory cytokine interleukin-1 (IL-1). Inhibition of IL...

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Detalles Bibliográficos
Autores principales: Pradillo, Jesus M., Murray, Katie N., Coutts, Graham A., Moraga, Ana, Oroz-Gonjar, Fernando, Boutin, Herve, Moro, Maria A., Lizasoain, Ignacio, Rothwell, Nancy J., Allan, Stuart M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325120/
https://www.ncbi.nlm.nih.gov/pubmed/27856349
http://dx.doi.org/10.1016/j.bbi.2016.11.013