Topical ocular delivery to laser-induced choroidal neovascularization by dual internalizing RGD and TAT peptide-modified nanoparticles

A nanoparticle (NP) was developed to target choroidal neovascularization (CNV) via topical ocular administration. The NPs were prepared through conjugation of internalizing arginine-glycine-aspartic acid RGD (iRGD; Ac-CCRGDKGPDC) and transactivated transcription (TAT) (RKKRRQRRRC) peptide to polymer...

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Detalles Bibliográficos
Autores principales: Chu, Yongchao, Chen, Ning, Yu, Huajun, Mu, Hongjie, He, Bin, Hua, Hongchen, Wang, Aiping, Sun, Kaoxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325139/
https://www.ncbi.nlm.nih.gov/pubmed/28260884
http://dx.doi.org/10.2147/IJN.S126865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325139/
https://www.ncbi.nlm.nih.gov/pubmed/28260884
http://dx.doi.org/10.2147/IJN.S126865

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