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Topical ocular delivery to laser-induced choroidal neovascularization by dual internalizing RGD and TAT peptide-modified nanoparticles
A nanoparticle (NP) was developed to target choroidal neovascularization (CNV) via topical ocular administration. The NPs were prepared through conjugation of internalizing arginine-glycine-aspartic acid RGD (iRGD; Ac-CCRGDKGPDC) and transactivated transcription (TAT) (RKKRRQRRRC) peptide to polymer...
Autores principales: | Chu, Yongchao, Chen, Ning, Yu, Huajun, Mu, Hongjie, He, Bin, Hua, Hongchen, Wang, Aiping, Sun, Kaoxiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325139/ https://www.ncbi.nlm.nih.gov/pubmed/28260884 http://dx.doi.org/10.2147/IJN.S126865 |
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