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Enhanced acarbose production by Streptomyces M37 using a two-stage fermentation strategy

In this work, we investigated the effect of pH on Streptomyces M37 growth and its acarbose biosynthesis ability. We observed that low pH was beneficial for cell growth, whereas high pH favored acarbose synthesis. Moreover, addition of glucose and maltose to the fermentation medium after 72 h of cult...

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Detalles Bibliográficos
Autores principales: Ren, Fei, Chen, Long, Xiong, Shuangli, Tong, Qunyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325187/
https://www.ncbi.nlm.nih.gov/pubmed/28234967
http://dx.doi.org/10.1371/journal.pone.0166985