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Enhanced acarbose production by Streptomyces M37 using a two-stage fermentation strategy
In this work, we investigated the effect of pH on Streptomyces M37 growth and its acarbose biosynthesis ability. We observed that low pH was beneficial for cell growth, whereas high pH favored acarbose synthesis. Moreover, addition of glucose and maltose to the fermentation medium after 72 h of cult...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325187/ https://www.ncbi.nlm.nih.gov/pubmed/28234967 http://dx.doi.org/10.1371/journal.pone.0166985 |