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Association of IFIH1 and pro-inflammatory mediators: Potential new clues in SLE-associated pathogenesis

Antiviral defenses are inappropriately activated in systemic lupus erythematosus (SLE) and association between SLE and the antiviral helicase gene, IFIH1, is well established. We sought to extend the previously reported association of pathogenic soluble mediators and autoantibodies with mouse Mda5 t...

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Detalles Bibliográficos
Autores principales: Munroe, Melissa E., Pezant, Nathan, Brown, Michael A., Fife, Dustin A., Guthridge, Joel M., Kelly, Jennifer A., Wiley, Graham, Gaffney, Patrick M., James, Judith A., Montgomery, Courtney G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325200/
https://www.ncbi.nlm.nih.gov/pubmed/28234905
http://dx.doi.org/10.1371/journal.pone.0171193