Cargando…

Association of IFIH1 and pro-inflammatory mediators: Potential new clues in SLE-associated pathogenesis

Antiviral defenses are inappropriately activated in systemic lupus erythematosus (SLE) and association between SLE and the antiviral helicase gene, IFIH1, is well established. We sought to extend the previously reported association of pathogenic soluble mediators and autoantibodies with mouse Mda5 t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Munroe, Melissa E., Pezant, Nathan, Brown, Michael A., Fife, Dustin A., Guthridge, Joel M., Kelly, Jennifer A., Wiley, Graham, Gaffney, Patrick M., James, Judith A., Montgomery, Courtney G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325200/ https://www.ncbi.nlm.nih.gov/pubmed/28234905 http://dx.doi.org/10.1371/journal.pone.0171193

Ejemplares similares

Expression and methylation data from SLE patient and healthy control blood samples subdivided with respect to ARID3a levels
por: Ward, Julie M., et al.
Publicado: (2016)

Roles of Pro- and Anti-Inflammatory Cytokines in the Pathogenesis of SLE
por: Su, Ding-Lei, et al.
Publicado: (2012)

Genetic and phenotypic spectrum associated with IFIH1 gain-of-function
por: Rice, Gillian I., et al.
Publicado: (2020)

Admixture Mapping in Lupus Identifies Multiple Functional Variants within IFIH1 Associated with Apoptosis, Inflammation, and Autoantibody Production
por: Molineros, Julio E., et al.
Publicado: (2013)

Strong viral associations with SLE among Filipinos
por: Vista, Evan S, et al.
Publicado: (2017)

Editorial: Mechanisms by Which SLE-Associated Genetic Variants Contribute to SLE Pathogenesis
por: Crispín, José C., et al.
Publicado: (2019)

Genetic Polymorphisms in Genes Involved in the Type I Interferon System (IFIH1/MDA-5, TNFAIP3/A20, and STAT4): Association with SLE Risk in Egyptian Children and Adolescents
por: Zedan, Mohamed M, et al.
Publicado: (2021)

The role of DNA in the pathogenesis of SLE
por: Pisetsky, DS
Publicado: (2001)

Reduced Expression of IFIH1 Is Protective for Type 1 Diabetes
por: Downes, Kate, et al.
Publicado: (2010)

Study of Transcriptional Effects in Cis at the IFIH1 Locus
por: Zouk, Hana, et al.
Publicado: (2010)

The Nasal Microbiome in ANCA-Associated Vasculitis: Picking the Nose for Clues on Disease Pathogenesis
por: Dekkema, G. J., et al.
Publicado: (2021)

Development and validation of a simple lupus severity index using ACR criteria for classification of SLE
por: Bello, Ghalib A, et al.
Publicado: (2016)

IFIH1 Contributes to M1 Macrophage Polarization in ARDS
por: Zhang, Shi, et al.
Publicado: (2021)

Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with Systemic Lupus Erythematosus
por: Cunninghame Graham, Deborah S., et al.
Publicado: (2011)

Multiple Correspondence Analysis and HLA-Associations of Organ Involvement in a Large Cohort of African-American and European-American Patients with Sarcoidosis
por: Rasmussen, Astrid, et al.
Publicado: (2023)

Enhancer histone-QTLs are enriched on autoimmune risk haplotypes and influence gene expression within chromatin networks
por: Pelikan, Richard C., et al.
Publicado: (2018)

COVID-19 Disease and Associated Thrombocytopenia: Pathogenesis and a Clue to the Etiology
por: Eissa, Adil Abozaid
Publicado: (2022)

A rare coding allele in IFIH1 is protective for psoriatic arthritis
por: Budu-Aggrey, Ashley, et al.
Publicado: (2017)

IFIH1 and DDX58 gene variants in pediatric rheumatic diseases
por: Raupov, Rinat, et al.
Publicado: (2023)

Multiple Autoantibodies Display Association with Lymphopenia, Proteinuria, and Cellular Casts in a Large, Ethnically Diverse SLE Patient Cohort
por: Lu, Rufei, et al.
Publicado: (2012)

Associates and predictors of pleurisy or pericarditis in SLE
por: Ryu, Seungwon, et al.
Publicado: (2017)

The rs1990760 polymorphism within the IFIH1 locus is not associated with Graves' disease, Hashimoto's thyroiditis and Addison's disease
por: Penna-Martinez, Marissa, et al.
Publicado: (2009)

Hereditary spastic paraplegia associated with a rare IFIH1 mutation: a case report and literature review
por: Liu, Nan, et al.
Publicado: (2019)

Is the Association of the Rare rs35667974 IFIH1 Gene Polymorphism With Autoimmune Diseases a Case of RNA Epigenetics?
por: Andreou, Athena, et al.
Publicado: (2023)

Association between Inflammation and Thrombotic Pathway Link with Pathogenesis of Depression and Anxiety in SLE Patients
por: Duca, Liliana, et al.
Publicado: (2023)

Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations
por: Wang, Chuan, et al.
Publicado: (2013)

Aicardi-Goutières syndrome due to a paternal mosaic IFIH1 mutation
por: Tüngler, Victoria, et al.
Publicado: (2019)

CD8+ T-Cells in Juvenile-Onset SLE: From Pathogenesis to Comorbidities
por: Ciurtin, Coziana, et al.
Publicado: (2022)

PTPN22 Association in Systemic Lupus Erythematosus (SLE) with Respect to Individual Ancestry and Clinical Sub-Phenotypes
por: Namjou, Bahram, et al.
Publicado: (2013)

MHC associations with clinical and autoantibody manifestations in European SLE
por: Morris, DL, et al.
Publicado: (2014)

Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients
por: James, Judith A., et al.
Publicado: (2019)

Genetic Association Study of TNFAIP3, IFIH1, IRF5 Polymorphisms with Polymyositis/Dermatomyositis in Chinese Han Population
por: Chen, Si, et al.
Publicado: (2014)

Molecular neurobiological clues to the pathogenesis of bipolar disorder
por: Harrison, Paul J
Publicado: (2016)

The Bronchus—The Clue to the Pathogenesis and Treatment of Pulmonary Tuberculosis?
por: Young, F. H.
Publicado: (1953)

Early clues regarding the pathogenesis of long-COVID
por: Peluso, Michael J., et al.
Publicado: (2022)

The epidemiology of inflammatory bowel disease: Clues to pathogenesis?
por: Borowitz, Stephen M.
Publicado: (2023)

Genetic studies provide clues on the pathogenesis of idiopathic pulmonary fibrosis
por: Kropski, Jonathan A., et al.
Publicado: (2013)

Associations of metabolic syndrome in SLE
por: Apostolopoulos, Diane, et al.
Publicado: (2020)

GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region
por: Armstrong, Don L., et al.
Publicado: (2014)

Looking for Cancer Clues in Publicly Accessible Databases
por: Medjahed, Djamel, et al.
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_skq3v4ioej4525c438hc10hafc