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Proof-of-Concept Randomized Trial of the Monoclonal Antibody GSK249320 Versus Placebo in Stroke Patients

BACKGROUND AND PURPOSE—: One class of poststroke restorative therapy focuses on promoting axon outgrowth by blocking myelin-based inhibitory proteins such as myelin-associated glycoprotein. The purpose of the current study was to extend preclinical and clinical findings of GSK249320, a humanized mon...

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Detalles Bibliográficos
Autores principales: Cramer, Steven C., Enney, Lori A., Russell, Colleen K., Simeoni, Monica, Thompson, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325241/
https://www.ncbi.nlm.nih.gov/pubmed/28228578
http://dx.doi.org/10.1161/STROKEAHA.116.014517