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CRISPR/Cas9 mediated chicken Stra8 gene knockout and inhibition of male germ cell differentiation
An efficient genome editing approach had been established to construct the stable transgenic cell lines in the domestic chicken (Gallus gallus domesticus) at present. Our objectives were to investigate gene function in the differentiation process of chicken embryonic stem cells (ESCs) into spermatog...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325261/ https://www.ncbi.nlm.nih.gov/pubmed/28234938 http://dx.doi.org/10.1371/journal.pone.0172207 |