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The effect of epigenetic silencing and TP53 mutation on the expression of DLL4 in human cancer stem disorder
The Li-Fraumeni Syndrome (LFS), a genetically rare heterogeneous cancer syndrome, is characterized primarily by a germline p53 (TP53) gene mutation. We recently discovered a balanced reciprocal chromosomal translocation t(11;15)(q23;q15) in the non-cancerous skin fibroblasts of a bilateral breast ca...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals LLC
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325341/ https://www.ncbi.nlm.nih.gov/pubmed/27542210 http://dx.doi.org/10.18632/oncotarget.11316 |