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Visceral fat adipocytes from obese and colorectal cancer subjects exhibit distinct secretory and ω6 polyunsaturated fatty acid profiles and deliver immunosuppressive signals to innate immunity cells

Obesity is a low-grade chronic inflammatory state representing an important risk factor for colorectal cancer (CRC). Adipocytes strongly contribute to inflammation by producing inflammatory mediators. In this study we investigated the role of human visceral fat adipocytes in regulating the functions...

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Detalles Bibliográficos
Autores principales: Del Cornò, Manuela, D'Archivio, Massimo, Conti, Lucia, Scazzocchio, Beatrice, Varì, Rosaria, Donninelli, Gloria, Varano, Barbara, Giammarioli, Stefania, De Meo, Simone, Silecchia, Gianfranco, Pennestrì, Francesco, Persiani, Roberto, Masella, Roberta, Gessani, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325349/
https://www.ncbi.nlm.nih.gov/pubmed/27494857
http://dx.doi.org/10.18632/oncotarget.10998