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DDA suppresses angiogenesis and tumor growth of colorectal cancer in vivo through decreasing VEGFR2 signaling

As angiogenesis is required for tumor growth and metastasis, suppressing angiogenesis is a promising strategy in limiting tumor progression. Vascular endothelial growth factor (VEGF)-A, a critical pro-angiogenic factor, has thus become an attractive target for therapeutic interventions in cancer. In...

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Detalles Bibliográficos
Autores principales: Huang, Shiu-Wen, Lien, Jin-Cherng, Kuo, Sheng-Chu, Huang, Tur-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325351/
https://www.ncbi.nlm.nih.gov/pubmed/27517319
http://dx.doi.org/10.18632/oncotarget.11152