Sphingosine-1-phosphate induced epithelial-mesenchymal transition of hepatocellular carcinoma via an MMP-7/syndecan-1/TGF-β autocrine loop

Sphingosine-1-phosphate (S1P) induces epithelial–mesenchymal transition (EMT) in hepatocellular carcinoma (HCC). However, its underlying mechanism remains largely unknown. In the present study, we investigated the correlation between S1P and syndecan-1 in HCC, the molecular mechanism involved, as we...

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Detalles Bibliográficos
Autores principales: Zeng, Ye, Yao, Xinghong, Chen, Li, Yan, Zhiping, Liu, Jingxia, Zhang, Yingying, Feng, Tang, Wu, Jiang, Liu, Xiaoheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325366/
https://www.ncbi.nlm.nih.gov/pubmed/27556509
http://dx.doi.org/10.18632/oncotarget.11450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325366/
https://www.ncbi.nlm.nih.gov/pubmed/27556509
http://dx.doi.org/10.18632/oncotarget.11450

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