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Sphingosine-1-phosphate induced epithelial-mesenchymal transition of hepatocellular carcinoma via an MMP-7/syndecan-1/TGF-β autocrine loop
Sphingosine-1-phosphate (S1P) induces epithelial–mesenchymal transition (EMT) in hepatocellular carcinoma (HCC). However, its underlying mechanism remains largely unknown. In the present study, we investigated the correlation between S1P and syndecan-1 in HCC, the molecular mechanism involved, as we...
Autores principales: | Zeng, Ye, Yao, Xinghong, Chen, Li, Yan, Zhiping, Liu, Jingxia, Zhang, Yingying, Feng, Tang, Wu, Jiang, Liu, Xiaoheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325366/ https://www.ncbi.nlm.nih.gov/pubmed/27556509 http://dx.doi.org/10.18632/oncotarget.11450 |
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