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Rab27A mediated by NF-κB promotes the stemness of colon cancer cells via up-regulation of cytokine secretion

Recent evidences have unveiled critical roles of cancer stem cells (CSCs) in tumorigenicity, but how interactions between CSC and tumor environments help maintain CSC initiation remains obscure. The small GTPases Rab27A regulates autocrine and paracrine cytokines by monitoring exocytosis of extracel...

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Detalles Bibliográficos
Autores principales: Feng, Feixue, Jiang, Yinghao, Lu, Huanyu, Lu, Xiaozhao, Wang, Shan, Wang, Lifeng, Wei, Mengying, Lu, Wei, Du, Zhichao, Ye, Zichen, Yang, Guodong, Yuan, Fang, Ma, Yanxia, Lei, Xiaoying, Lu, Zifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325368/
https://www.ncbi.nlm.nih.gov/pubmed/27556511
http://dx.doi.org/10.18632/oncotarget.11454