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Rab27A mediated by NF-κB promotes the stemness of colon cancer cells via up-regulation of cytokine secretion
Recent evidences have unveiled critical roles of cancer stem cells (CSCs) in tumorigenicity, but how interactions between CSC and tumor environments help maintain CSC initiation remains obscure. The small GTPases Rab27A regulates autocrine and paracrine cytokines by monitoring exocytosis of extracel...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325368/ https://www.ncbi.nlm.nih.gov/pubmed/27556511 http://dx.doi.org/10.18632/oncotarget.11454 |