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Mel-18 negatively regulates stem cell-like properties through downregulation of miR-21 in gastric cancer

Mel-18, a polycomb group protein, has been reported to act as a tumor suppressor and be down-regulated in several human cancers including gastric cancer. It was also found that Mel-18 negatively regulates self-renewal of hematopoietic stem cells and breast cancer stem cells (CSCs). This study aimed...

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Detalles Bibliográficos
Autores principales: Wang, Xiao-Feng, Zhang, Xiao-Wei, Hua, Rui-Xi, Du, Yi-Qun, Huang, Ming-Zhu, Liu, Yong, Cheng, Yu Fang, Guo, Wei-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325369/
https://www.ncbi.nlm.nih.gov/pubmed/27542229
http://dx.doi.org/10.18632/oncotarget.11221