Control of translational activation by PIM kinase in activated B-cell diffuse large B-cell lymphoma confers sensitivity to inhibition by PIM447

The PIM family kinases promote growth and survival of tumor cells and are expressed in a wide variety of human cancers. Their potential as therapeutic targets, however, is complicated by overlapping activities with multiple other pathways and remains poorly defined in most clinical scenarios. Here w...

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Detalles Bibliográficos
Autores principales: Peters, Tara L., Li, Lingxiao, Tula-Sanchez, Ana A., Pongtornpipat, Praechompoo, Schatz, Jonathan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325370/
https://www.ncbi.nlm.nih.gov/pubmed/27556513
http://dx.doi.org/10.18632/oncotarget.11457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325370/
https://www.ncbi.nlm.nih.gov/pubmed/27556513
http://dx.doi.org/10.18632/oncotarget.11457

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