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Epigenetic changes in localized gastric cancer: the role of RUNX3 in tumor progression and the immune microenvironment
Gastric cancer (GC) pathogenesis involves genetic, epigenetic and environmental factors. Epigenetic alterations, such as DNA methylation are considered pivotal in the inactivation of tumor-related genes. We assessed a methylation panel of 5 genes to study their association to GC progression and micr...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325374/ https://www.ncbi.nlm.nih.gov/pubmed/27566570 http://dx.doi.org/10.18632/oncotarget.11520 |