Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer

Breast cancer arising in female BRCA1 mutation carriers is characterized by an aggressive phenotype and early age of onset. We performed tandem mass spectrometry-based proteomics of secretomes and exosome-like extracellular vesicles from BRCA1-deficient and BRCA1-proficient murine breast tumor model...

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Detalles Bibliográficos
Autores principales: Warmoes, Marc, Lam, Siu W., van der Groep, Petra, Jaspers, Janneke E., Smolders, Yvonne H.C.M., de Boer, Leon, Pham, Thang V., Piersma, Sander R., Rottenberg, Sven, Boven, Epie, Jonkers, Jos, van Diest, Paul J., Jimenez, Connie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325383/
https://www.ncbi.nlm.nih.gov/pubmed/27566577
http://dx.doi.org/10.18632/oncotarget.11535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325383/
https://www.ncbi.nlm.nih.gov/pubmed/27566577
http://dx.doi.org/10.18632/oncotarget.11535

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