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Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer
Breast cancer arising in female BRCA1 mutation carriers is characterized by an aggressive phenotype and early age of onset. We performed tandem mass spectrometry-based proteomics of secretomes and exosome-like extracellular vesicles from BRCA1-deficient and BRCA1-proficient murine breast tumor model...
Autores principales: | Warmoes, Marc, Lam, Siu W., van der Groep, Petra, Jaspers, Janneke E., Smolders, Yvonne H.C.M., de Boer, Leon, Pham, Thang V., Piersma, Sander R., Rottenberg, Sven, Boven, Epie, Jonkers, Jos, van Diest, Paul J., Jimenez, Connie R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325383/ https://www.ncbi.nlm.nih.gov/pubmed/27566577 http://dx.doi.org/10.18632/oncotarget.11535 |
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