Novel synthetic cyclic integrin αvβ3 binding peptide ALOS4: antitumor activity in mouse melanoma models

ALOS4, a unique synthetic cyclic peptide without resemblance to known integrin ligand sequences, was discovered through repeated biopanning with pIII phage expressing a disulfide-constrained nonapeptide library. Binding assays using a FITC-labeled analogue demonstrated selective binding to immobiliz...

Descripción completa

Detalles Bibliográficos
Autores principales: Yacobovich, Shiri, Tuchinsky, Lena, Kirby, Michael, Kardash, Tetiana, Agranyoni, Oryan, Nesher, Elimelech, Redko, Boris, Gellerman, Gary, Tobi, Dror, Gurova, Katerina, Koman, Igor, Fabian, Osnat Ashur, Pinhasov, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325384/
https://www.ncbi.nlm.nih.gov/pubmed/27556860
http://dx.doi.org/10.18632/oncotarget.11363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325384/
https://www.ncbi.nlm.nih.gov/pubmed/27556860
http://dx.doi.org/10.18632/oncotarget.11363

Ejemplares similares