Leucine deprivation inhibits proliferation and induces apoptosis of human breast cancer cells via fatty acid synthase

Substantial studies on fatty acid synthase (FASN) have focused on its role in regulating lipid metabolism and researchers have a great interest in treating cancer with dietary manipulation of amino acids. In the current study, we found that leucine deprivation caused the FASN-dependent anticancer ef...

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Detalles Bibliográficos
Autores principales: Xiao, Fei, Wang, Chunxia, Yin, Hongkun, Yu, Junjie, Chen, Shanghai, Fang, Jing, Guo, Feifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325395/
https://www.ncbi.nlm.nih.gov/pubmed/27579768
http://dx.doi.org/10.18632/oncotarget.11626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325395/
https://www.ncbi.nlm.nih.gov/pubmed/27579768
http://dx.doi.org/10.18632/oncotarget.11626

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