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Leucine deprivation inhibits proliferation and induces apoptosis of human breast cancer cells via fatty acid synthase
Substantial studies on fatty acid synthase (FASN) have focused on its role in regulating lipid metabolism and researchers have a great interest in treating cancer with dietary manipulation of amino acids. In the current study, we found that leucine deprivation caused the FASN-dependent anticancer ef...
Autores principales: | Xiao, Fei, Wang, Chunxia, Yin, Hongkun, Yu, Junjie, Chen, Shanghai, Fang, Jing, Guo, Feifan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325395/ https://www.ncbi.nlm.nih.gov/pubmed/27579768 http://dx.doi.org/10.18632/oncotarget.11626 |
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