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RSPOs facilitated HSC activation and promoted hepatic fibrogenesis

Roof plate-specific spondin (RSPO) proteins are potent Wnt pathway agonists and involve in a broad range of developmental and physiological processes. This study investigated the activities and mechanisms of RSPOs in liver fibrogenesis, especially in hepatic stellate cell (HSC) activation. HSC activ...

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Detalles Bibliográficos
Autores principales: Yin, Xinguang, Yi, Huixing, Wang, Linlin, Wu, Wanxin, Wu, Xiaojun, Yu, Linghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325402/
https://www.ncbi.nlm.nih.gov/pubmed/27572318
http://dx.doi.org/10.18632/oncotarget.11654