RSL3 and Erastin differentially regulate redox signaling to promote Smac mimetic-induced cell death

Redox mechanisms play an important role in the control of various signaling pathways. Here, we report that Second mitochondrial activator of caspases (Smac) mimetic-induced cell death is regulated by redox signaling. We show that RSL3, a glutathione (GSH) peroxidase (GPX) 4 inhibitor, or Erastin, an...

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Detalles Bibliográficos
Autores principales: Dächert, Jasmin, Schoeneberger, Hannah, Rohde, Katharina, Fulda, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325403/
https://www.ncbi.nlm.nih.gov/pubmed/27588473
http://dx.doi.org/10.18632/oncotarget.11687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325403/
https://www.ncbi.nlm.nih.gov/pubmed/27588473
http://dx.doi.org/10.18632/oncotarget.11687

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