Transcriptomic and functional pathways analysis of ascorbate-induced cytotoxicity and resistance of Burkitt lymphoma

Ascorbate is a pro-oxidant that generates hydrogen peroxide–dependent cytotoxity in cancer cells without adversely affecting normal cells. To determine the mechanistic basis for this phenotype, we selected Burkitt lymphoma cells resistant to ascorbate (JLPR cells) and their ascorbate-sensitive paren...

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Detalles Bibliográficos
Autores principales: Pei, Zenglin, Zhang, Xuan, Ji, Chunxia, Liu, Song-Mei, Wang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325416/
https://www.ncbi.nlm.nih.gov/pubmed/27590508
http://dx.doi.org/10.18632/oncotarget.11740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325416/
https://www.ncbi.nlm.nih.gov/pubmed/27590508
http://dx.doi.org/10.18632/oncotarget.11740

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