Modeling of signaling crosstalk-mediated drug resistance and its implications on drug combination

The efficacy of pharmacological perturbation to the signaling transduction network depends on the network topology. However, whether and how signaling dynamics mediated by crosstalk contributes to the drug resistance are not fully understood and remain to be systematically explored. In this study, m...

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Detalles Bibliográficos
Autores principales: Sun, Xiaoqiang, Bao, Jiguang, You, Zhuhong, Chen, Xing, Cui, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325420/
https://www.ncbi.nlm.nih.gov/pubmed/27590512
http://dx.doi.org/10.18632/oncotarget.11745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325420/
https://www.ncbi.nlm.nih.gov/pubmed/27590512
http://dx.doi.org/10.18632/oncotarget.11745

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