PARP3 controls TGFβ and ROS driven epithelial-to-mesenchymal transition and stemness by stimulating a TG2-Snail-E-cadherin axis

Several members of the Poly(ADP-ribose) polymerase (PARP) family are essential regulators of genome integrity, actively prospected as drug targets for cancer therapy. Among them, PARP3 is well characterized for its functions in double-strand break repair and mitotis. Here we report that PARP3 also p...

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Detalles Bibliográficos
Autores principales: Karicheva, Olga, Rodriguez-Vargas, José Manuel, Wadier, Nadège, Martin-Hernandez, Kathline, Vauchelles, Romain, Magroun, Najat, Tissier, Agnès, Schreiber, Valérie, Dantzer, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325429/
https://www.ncbi.nlm.nih.gov/pubmed/27579892
http://dx.doi.org/10.18632/oncotarget.11627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325429/
https://www.ncbi.nlm.nih.gov/pubmed/27579892
http://dx.doi.org/10.18632/oncotarget.11627

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