Regorafenib (Stivarga) pharmacologically targets epithelial-mesenchymal transition in colorectal cancer

Epithelial-to-mesenchymal transition (EMT) is well-known to evoke cancer invasion/metastasis, leading to a high frequency of mortality in patients with metastatic colorectal cancer (mCRC). Protein tyrosine phosphatase (PTPase)-targeted therapy has been identified as a novel cancer therapeutic. Previ...

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Detalles Bibliográficos
Autores principales: Fan, Li-Ching, Teng, Hao-Wei, Shiau, Chung-Wai, Tai, Wei-Tien, Hung, Man-Hsin, Yang, Shung-Haur, Jiang, Jeng-Kai, Chen, Kuen-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325431/
https://www.ncbi.nlm.nih.gov/pubmed/27580057
http://dx.doi.org/10.18632/oncotarget.11636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325431/
https://www.ncbi.nlm.nih.gov/pubmed/27580057
http://dx.doi.org/10.18632/oncotarget.11636

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