Cargando…

Loss of Par3 promotes lung adenocarcinoma metastasis through 14-3-3ζ protein

Partitioning defective protein 3 (Par3) can activate the Tiam1/Rac pathway to inhibit invasion and metastasis in many cancers; however, the role of Par3 in lung adenocarcinoma remains unknown. Here we show that Par3 is downregulated in lung adenocarcinoma tissues and is associated with higher rates...

Descripción completa

Detalles Bibliográficos
Autores principales: Tong, Song, Xia, Tian, Fan, Kai, Jiang, Ke, Zhai, Wei, Li, Jing-Song, Wang, Si-Hua, Wang, Jian-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325440/
https://www.ncbi.nlm.nih.gov/pubmed/27588399
http://dx.doi.org/10.18632/oncotarget.11728