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Suppressive role of myeloid-derived suppressor cells (MDSCs) in the microenvironment of breast cancer and targeted immunotherapies

Myeloid-derived suppressor cells (MDSCs) play a pivotal role in promoting tumor growth and metastasis and can even decrease the efficacy of immunotherapy. In breast cancer, MDSCs are recruited mainly by breast cancer cells to form a tumor-favoring microenvironment to suppress the anti-tumor immune r...

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Detalles Bibliográficos
Autores principales: Shou, Dawei, Wen, Liang, Song, Zhenya, Yin, Jian, Sun, Qiming, Gong, Weihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325458/
https://www.ncbi.nlm.nih.gov/pubmed/27542274
http://dx.doi.org/10.18632/oncotarget.11352