RAC1b overexpression stimulates proliferation and NF-kB-mediated anti-apoptotic signaling in thyroid cancer cells

Overexpression of tumor-associated RAC1b has been recently highlighted as one of the most promising targets for therapeutic intervention in colon, breast, lung and pancreatic cancer. RAC1b is a hyperactive variant of the small GTPase RAC1 and has been recently shown to be overexpressed in a subset o...

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Detalles Bibliográficos
Autores principales: Faria, Márcia, Matos, Paulo, Pereira, Teresa, Cabrera, Rafael, Cardoso, Bruno A., Bugalho, Maria João, Silva, Ana Luísa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325471/
https://www.ncbi.nlm.nih.gov/pubmed/28234980
http://dx.doi.org/10.1371/journal.pone.0172689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325471/
https://www.ncbi.nlm.nih.gov/pubmed/28234980
http://dx.doi.org/10.1371/journal.pone.0172689

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