Whole genome expression profiling associates activation of unfolded protein response with impaired production and release of epinephrine after recurrent hypoglycemia

Recurrent hypoglycemia can occur as a major complication of insulin replacement therapy, limiting the long-term health benefits of intense glycemic control in type 1 and advanced type 2 diabetic patients. It impairs the normal counter-regulatory hormonal and behavioral responses to glucose deprivati...

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Detalles Bibliográficos
Autores principales: Kim, Juhye Lena, La Gamma, Edmund F., Estabrook, Todd, Kudrick, Necla, Nankova, Bistra B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325535/
https://www.ncbi.nlm.nih.gov/pubmed/28234964
http://dx.doi.org/10.1371/journal.pone.0172789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325535/
https://www.ncbi.nlm.nih.gov/pubmed/28234964
http://dx.doi.org/10.1371/journal.pone.0172789

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