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Whole genome expression profiling associates activation of unfolded protein response with impaired production and release of epinephrine after recurrent hypoglycemia
Recurrent hypoglycemia can occur as a major complication of insulin replacement therapy, limiting the long-term health benefits of intense glycemic control in type 1 and advanced type 2 diabetic patients. It impairs the normal counter-regulatory hormonal and behavioral responses to glucose deprivati...
Autores principales: | Kim, Juhye Lena, La Gamma, Edmund F., Estabrook, Todd, Kudrick, Necla, Nankova, Bistra B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325535/ https://www.ncbi.nlm.nih.gov/pubmed/28234964 http://dx.doi.org/10.1371/journal.pone.0172789 |
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