Genome-wide effects of MELK-inhibitor in triple-negative breast cancer cells indicate context-dependent response with p53 as a key determinant

Triple-negative breast cancer (TNBC) is an aggressive, highly recurrent breast cancer subtype, affecting approximately one-fifth of all breast cancer patients. Subpopulations of treatment-resistant cancer stem cells within the tumors are considered to contribute to disease recurrence. A potential dr...

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Detalles Bibliográficos
Autores principales: Simon, Marisa, Mesmar, Fahmi, Helguero, Luisa, Williams, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325553/
https://www.ncbi.nlm.nih.gov/pubmed/28235006
http://dx.doi.org/10.1371/journal.pone.0172832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325553/
https://www.ncbi.nlm.nih.gov/pubmed/28235006
http://dx.doi.org/10.1371/journal.pone.0172832

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