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Phase modulation of insulin pulses enhances glucose regulation and enables inter-islet synchronization

Insulin is secreted in a pulsatile manner from multiple micro-organs called the islets of Langerhans. The amplitude and phase (shape) of insulin secretion are modulated by numerous factors including glucose. The role of phase modulation in glucose homeostasis is not well understood compared to the o...

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Detalles Bibliográficos
Autores principales: Lee, Boah, Song, Taegeun, Lee, Kayoung, Kim, Jaeyoon, Han, Seungmin, Berggren, Per-Olof, Ryu, Sung Ho, Jo, Junghyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325581/
https://www.ncbi.nlm.nih.gov/pubmed/28235104
http://dx.doi.org/10.1371/journal.pone.0172901