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Phase modulation of insulin pulses enhances glucose regulation and enables inter-islet synchronization
Insulin is secreted in a pulsatile manner from multiple micro-organs called the islets of Langerhans. The amplitude and phase (shape) of insulin secretion are modulated by numerous factors including glucose. The role of phase modulation in glucose homeostasis is not well understood compared to the o...
Autores principales: | Lee, Boah, Song, Taegeun, Lee, Kayoung, Kim, Jaeyoon, Han, Seungmin, Berggren, Per-Olof, Ryu, Sung Ho, Jo, Junghyo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325581/ https://www.ncbi.nlm.nih.gov/pubmed/28235104 http://dx.doi.org/10.1371/journal.pone.0172901 |
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